Brain tumours effectively treated by injecting patients with viruses to activate the immune system (cancer)
Viral stimulation of the human immune response could be employed to treat cancers.
The presence of the virus – which seeks out cancer cells – counteracts this, stimulating the body’s natural defences into action, and is now the subject of a wider clinical trial.
By introducing viruses into brain tumours the scientists were able to essentially “switch on” the immune system’s response to the brain cancer in the nine patients involved in the trial.
There was evidence the virus had stimulated an immune response that attacked tumours, even those found deep within the brain.
The presence of the virus itself, on the other hand, caused patients to report nothing more serious than flu-like side effects.
The major breakthrough in this trial was the realisation that the viruses can pass through the “blood-brain barrier”.
The results of this work were published in the journal Science Translational Medicine.
Professor Susan Short, an oncologist at the University of Leeds, who led the trial said: “For a long time, there have not been many new developments that we could offer patients but the research that is happening at the University of Leeds and elsewhere is beginning to offer a new approach.”
Brain tumours effectively treated by injecting patients with viruses
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Viral stimulation of the human immune response could be employed to treat cancers.
The presence of the virus – which seeks out cancer cells – counteracts this, stimulating the body’s natural defences into action, and is now the subject of a wider clinical trial.
By introducing viruses into brain tumours the scientists were able to essentially “switch on” the immune system’s response to the brain cancer in the nine patients involved in the trial.
There was evidence the virus had stimulated an immune response that attacked tumours, even those found deep within the brain.
The presence of the virus itself, on the other hand, caused patients to report nothing more serious than flu-like side effects.
The major breakthrough in this trial was the realisation that the viruses can pass through the “blood-brain barrier”.
The results of this work were published in the journal Science Translational Medicine.
Professor Susan Short, an oncologist at the University of Leeds, who led the trial said: “For a long time, there have not been many new developments that we could offer patients but the research that is happening at the University of Leeds and elsewhere is beginning to offer a new approach.”
Brain tumours effectively treated by injecting patients with viruses
Innovation Future Forum
» Innovative ideas to solve your challenges
» Q&A about creativity and innovation
» and much more.
Modern Online Innovation and Creativity Training Courses in the UK
Powered by Innovation Future Specialist, the UK's most modern innovation provider.
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